Isolation and Characterization of Prostate Stem Cells
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چکیده
Abstract Based on the unique capacity of the rodent prostate to undergo seemingly endless rounds of androgen cycling in response to castration and androgen addback, the prostate has been proposed to contain long-term self-renewing stem cells. However the prospective isolation and characterization of stem-like cells from rodent and human prostate tissue has only been described over the last 2 decades. Several models of epithelial homeostasis in the adult prostate have been proposed based on either the presence of a multipotent tissue stem cell that differentiates through a series of intermediate developmental stages or the coexistence of Chapter 2 Isolation and Characterization of Prostate Stem Cells
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تاریخ انتشار 2017